I have estimated the point spread for every game for the 2015 NFL season. See image below. The teams on the left column are home teams and the teams on the top row are away teams (does not factor London games differently).
Estim. spread via 2014 reg. season net ppg, +2.5 for home team, -2.5 for divisional game.
This chart won’t tell you which teams to bet on but it’s a great ranking system and it the data can be used to give estimations of win totals and which team has the easier schedule within their division.
Regards,
The Bozeek
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